Immunology

Rapamycin (Sirolimus) Toxicity

Rapamycin is a macrolide with an immunosuppressive property through mTOR inhibition. This makes the drug useful to prevent kidney transplant rejection. Mnemonic: “HIP hop RAPper” H – Hyperlipidemia I – Insulin Resistance P – Pancytopenia hop RAPper – RAPamycin